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Shingles is a painful skin rash, often with blisters. It is also called Herpes Zoster.

A shingles rash usually appears on one side of the face or body and lasts from 2 to 4 weeks. Its main symptom is pain, which can be quite severe. Other symptoms of shingles can include fever, headache, chills, and upset stomach. Very rarely, a shingles infection can lead to pneumonia, hearing problems, blindness, brain inflammation (encephalitis) or death.

For about 1 person in 5, severe pain can continue even after the rash clears up. This is called post-herpetic neuralgia.

Shingles is caused by the Varicella Zoster virus, the same virus that causes chickenpox. Only someone who has had a case of chickenpox - or gotten chickenpox vaccine - can get shingles. The virus stays in your body. It can reappear many years later to cause a case of shingles.

You can't catch shingles from another person with shingles. However, a person who has never had chickenpox (or chickenpox vaccine) could get chickenpox from someone with shingles. This is not very common.

Shingles is far more common in people 50 and older than in younger people. It is also more common in people whose immune systems are weakened because of a disease such as cancer, or drugs such as steroids or chemotherapy. At least 1 million people a year in the United States get shingles.

A vaccine for shingles was licensed in 2006. In clinical trials, the vaccine prevented shingles in about half of people 60 years of age and older. It can also reduce the pain associated with shingles.

Some people should not get shingles vaccine or should wait.
A person should not get shingles vaccine who:

has ever had a life-threatening allergic reaction of gelatin, the antibiotic neomycin, or any other component of shingles vaccine. Tell your doctor if you have any severe allergies.
has a weakened immune system because of:

HIV/AIDS or another disease that affects the immune system,
treatment with drugs that affect the immune system, such as steroids,
cancer treatment such as radiation or chemotherapy,
a history of cancer affecting the bone marrow of lymphatic system, such as leukemia or lymphoma.

has active, untreated tuberculosis.
is pregnant, or might be pregnant. Women should not become pregnant until at least three months after getting shingles vaccine.

Someone with a minor illness, such as a cold, may be vaccinated. But anyone who is moderately or severely ill should usually wait until they recover before getting the vaccine. This includes anyone with a temperature of 101.3 degrees F. or higher.

A vaccine, like any medicine, could possibly cause serious problems, such as severe allergic reactions. However, the risk of a vaccine causing serious harm, or death, is extremely small.

Like all vaccines, shingles vaccine is being closely monitored for unusual or severe problems.

Any unusual condition, such as high fever or behavior changes. Signs of a serious allergic reaction can include difficulty breathing, hoarseness or wheezing, hives, paleness, weakness, a fast heart beat or dizziness. These usually occur within the first few hours after vaccination.

Call a doctor, or get the person to a doctor right away.
Tell your doctor what happened, the date and time it happened, and when the vaccination was given.
Ask your doctor, nurse, or health department to report the reaction by filing a Vaccine Adverse Event Reporting System form (VAERS).

Or you can file this report through the VAERS web site at www.vaers.hhs.gov or by calling 1-800-822-7967.

Your provider can give you the vaccine package insert or suggest other sources of information.
Call your local or state health department.
Contact the Centers for Disease Control and Prevention (CDC):
- Call 1-800-232-4636 (1-800-CDC-INFO)
- Visit CDC's web site at http://www.cdc.gov/vaccines/